Endocrine Abstracts

Introduction: Obesity is recognized as a risk factor for cardiovascular diseases. She can be associated with cardio-metabolic diseases. The objective of our study was to determine the metabolic profile of our obese adults.Materials and methods: This is a descriptive cross-sectional study involving obese adults consulting the service of Endocrinology of Sfax, Hedi Chaker University Hospital in 2023.Results: We recruited 40 obese pat...

Introduction: Cardiothyreosis is the consequence of the effects of excess free thyroid hormones on the vascular wall and myocardium. This complication is the most serious aspect of hyperthyroidism. Rhythm disorders and heart failure are the most frequently noted. The prevalence of coronary insufficiency is lower. The aim of this study is to evaluate the characteristics of coronary insufficiency in patients with hyperthyroidism.Method: This is a retrospec...

Introduction: Inslinomas are the most common cause of hypoglycemia resulting from endogenous hyperinsulinism. Although rare, they have the potential to produce metabolic derangements, necessitating early diagnosis. The aim of our study was to determine the clinical manifestations, diagnostic methods, treatments used and results of patients with insulinoma.Patients and methods: It’s a retrospective study including 9 patients with insulinoma, diagnose...

Introduction: Pheochromocytoma occurs in 0.1–5.7% of patients with Neurofibromatosis type 1(NF1). We report two cases of adrenal pheochromocytoma in patients with NF1.Observation: A 46 year-old male was admitted to our department for further examinations of an adrenal mass. The CT-scan showed two well-defined right adrenal masses measuring each 128×87×86 mm and 60×52×37 mm with central necrosis and calcifications in the biggest o...

Introduction: The pituitary stalk is the target of various congenital or acquired pathologies. In this context we report a cohort of 28 patients with pathology of the pituitary stalk to analyze their clinical, hormonal and radiological characteristics.Results: The average age of our patients was 28 years with extremes ranging from (15 to 64); Male dominance was noted in 60% of cases. The reason for consultation was either a staturo delay or a pubertal de...

Introduction: The quality of assay methods for HbA1c assessment has importantly improved last decades, however analytical interferences due to variants of hemoglobin remain of matter vigilance. Immunological interferences, although no longer described, may also occur.Observation: A 84-years-old woman without significant medical history was explored for polyneuropathy. Additional investigation as HbA1c was requested. As no value of HbA1c was obtained when...

Introduction: Turner syndrome (ST) affects 1/2500–1/4000 of female births, its association with congenital malformations is traditional, however the coexistence of hypopituitarism is exceptional. In this context, we report 6 patients; including 3 belonging to the same family and in whom the association of anterior pituitary insufficiency (IAH) to a ST was confirmed.Results: The average age of our patients was 17.2 years (11–31). The ST was sele...

IntroductionRecent studies in patients with Addison’s disease have shown that this condition, even if treated, is fraught with significant morbidity and even excess mortality. The objective of our study was to determine the deleterious effects of long-term glucocorticoid replacement mainly on the metabolic level.MethodsRetrospective study, carried out at the Endocrinology and Diabetology Department of H&...

IntroductionMitochondrial diabetes (DM) is characterized by a broad spectrum of phenotypic and genotypic involvement. Among 86 patients with DM, we chose to study the peculiarities of syndromic DM diagnosed in three families in order to be able to establish a correlation between this diversity of phenotypic expression and the biomolecular substratum of the mitochondrial genome.ResultsThese are four patients (...

Introduction Hypothyroidism (HT) is widespread in all age groups particularly within the increasing elderly population while its diagnosis is challenging owing to extremely varied and atypical symptoms. The objective of this study is to outline the clinical and biochemical features of HT and determine its main etiologies in a geriatric population. Methods We reviewed the medical charts of 53 patients aged 65 ...